Multivariate MAPIT Analysis

Functions for the marginal epistasis analysis.

mvmapit()

Multivariate MArginal ePIstasis Test (mvMAPIT)

LT-MAPIT Analysis

Functions for the marginal epistasis analysis of case-control traits.

binary_to_liability()

Convert binary traits to liabilities for low prevalence

Combining P-values

Functions for combining the variance component p-values.

fishers_combined()

Fisher's combine method on mvmapit return

harmonic_combined()

Harmonic mean p combine method on mvmapit return

cauchy_combined()

Cauchy p combine method on mvmapit return

Simulations

Functions for simulating quantitative traits with pairwise epistasis.

simulate_traits()

Simulate phenotye data

Simulated Data Examples

Data structures with simulated genotype, trait, and analysis data.

simulated_data

Genotype and trait data with epistasis.

mvmapit_data

Multivariate MAPIT analysis and exhaustive search analysis.

Real Data Examples

Data structures with results from real applications.

phillips_data

Multivariate MAPIT analysis of binding affinities in broadly neutralizing antibodies.