Returns a Seurat object that contains additional (fake) RNA expression counts. — get_seurat_obj_with_artificial

Given a Seurat object, returns a new Seurat object whose RNA expression counts includes the variable features from the original object and an equal number of artificial features.

Usage

get_seurat_obj_with_artificial_variables(
  seurat_obj,
  assay = "RNA",
  null_method = "ZIP",
  verbose = TRUE,
  cores
)

Arguments

seurat_obj: A Seurat object containing RNA expression counts.
assay: The assay to generate artificial variables from.
null_method: The generating distribution for the synthetic null variables (ZIP, NB, ZIP-copula, NB-copula)
verbose: Whether or not to show logging.
cores: The number of cores to use in generating synthetic null variables.

Value

A Seurat object that contains the original variable features and an equal number of artificial features.